Work Sheet 4
Amino Acids/Proteins
1. List the two functional
groups every amino acid posses.
2. Classify each
amino acid according to the chemical nature of its side chain.
3. Draw the reaction
in which two amino acids join to form a peptide bond.
4. Explain how a polypeptide can be hydrophobic,
hydrophilic or amphiphilic based on its amino acid sequence (primary structure).
5. Define secondary structure of proteins and describe the two most common types
of secondary structure.
6. Explain why proline is incompatible with an a-helix.
7. Define tertiary and quaternary structure
and explain how the hydrophobic effect
is a major driving force in the conformation
of proteins in aqueous environments.
Protein Synthesis and Maturation
1. Define the terms: genetic code, codon, anticodon, degenaracy, wobble, charged tRNA and translation.
2. List the steps and state the function of amino acid activation.
3. List the types of RNA used in translation and state their functions.
4. State the function of the ribosome in translation and list its major components.
5. List some antibiotics and toxins that inhibit synthesis.