Work Sheet 7
Myoglobin / Hemoglobin
1. Diagram the basic structural features of
myoglobin (Mb) and list the important
differences between myoglobin and hemoglobin
(Hb).
2. Diagram the iron-heme complex (detailed structure of heme not necessary) and describe
how it binds oxygen with the aid of residues in the Mb or Hb protein chain.
3. Discuss the binding
of carbon monoxide to the iron-heme complex.
4. Draw a simple oxygen affinity curve for myoglobin, which exists as a monomer.
© Sturm 2016