Biochemistry I, CHE 450

MW, Section -30

Instructor: Dr. Noel Sturm, SI 311


Course Organization and Policies:

1. Prerequisites: (a) General Chemistry (1 year) and (b) Organic Chemistry w/ Laboratory (1 year or a 1 semester survey course w/ lab) and (c) Quantitative Analysis (may NOT be taken concurrently w/ Biochemistry 450).

2. REQUIRED Text: Lehninger: Principles of Biochemistry, 8th Edition; Authors: Nelson and Cox

We will be Using the myCSUDH-ImmediateAccess- program.

How Does It Work?

The required course ebook will be available through BlackBoard in a digital format .

You will receive Free Access on the first day of classes.

Discounted pricing, $89.99, has been negotiated with publishers.

Students will have until Friday, February 17th, 2023 to opt out of the program..

After the opt-out deadline, any students who has not opted out will be charged on their CSUDH student account by the university, allowing more time to pay for the required material.

Here is a link from the publisher, Macmillan, that provides ISBN information for the text book and Sapling Learning.

Lehninger and Sapling

3. The reading list consistes of links (see below) for Lehninger that highlight the sections and sub-sections of each chapter that are important for understanding the chemistry of biological systems and are relevant to the questions you will be asked in the homework and on the exams.


4. Power Point Slides: The power point slides are on-line, arranged via lecture topic, see below. Examination questions will be derived directly from the readings, power point slides and homework. There are also additional .html files provided to give an alternative presentation of the material.


5. On-Line and On-Campus Sessions: We will meet on-line every Monday 10:00AM-11:15AM, using Class Collaborate Ultra, on-campus every Wednesday 10:00-11:15AM, WH D-165 and on-line every Friday, by appointment, 10:00AM-11:15AM for Office Hours, using Class Collaborate Ultra. We will discuss lecture material, do quick thinks and answer questions. It is very important that you attend all of the on-line sessions in order to succeed in this course. You must have a working computer, reliable internet connectivity and browser is an important requirement, please use Firefox 2.0.x or higher.


Instructions for Class Collaborate Ultra:


In Blackboard:


<Class Collaborate Ultra

<Click-on the "Session"

<Click-on "Join Room"


6.Examinations: There will be four multiple choice examinations (see syllabus for specific dates) each worth 99 points. Absolutely NO make-up exams will be given. All examinations will be on-line through Bb Collaborate Ultra using the Respondus Lockdown Browser.


7. Final Exam: The final exam (100 pts), will be on-line through Bb Collaborate Ultra using the Respondus Lockdown Browser and for section -30 is scheduled for Monday, May 15th, 2023, 1:00PM-3:00PM.


8. Homework:

9. The Goal of this course is to understand and outline Proteins, Enzymes, Vitamins, Membranes and all of the Carbohydrate Metabolic Pathways.


10. Grading Criteria: Letter grades are based on the following point distribution. Grades are criterion-referenced not norm-referenced; each student has an equal opportunity meet the criteria charted below:


Homework 220 pts
Respondus Test Question 4 pts
Exams 396 pts
Final Exam 100 pts
Total 720 pts





























11. Case Studies/Clinical Correlates: Related directly to the general biochemical principles being taught are intended to give "real-life" significance to the biochemistry experience and should be printed from the web site.

12. Course Description: The chemistry of amino acids and proteins; the chemistry and metabolism of carbohydrates and lipids; energetics in living systems.  The course is taught with a medical emphasis and covers peptides, proteins, myoglobin/hemoglobin, enzymes, vitamins, catecholamines and metabolism, as well as, clinical correlates and case studies.

13. Academic Integrity Statement
The university is a community of learners bonded together by the search for knowledge; the pursuit of personal, social, cultural, physical, and intellectual development; and the desire for the liberating effects of an advanced education. California State University, Dominguez Hills (CSUDH) has a culture--an academic culture--shared with other universities and colleges across the nation. Integral to that culture is a set of values such as academic freedom, dedication to teaching and learning, diversity, civility toward others, and academic integrity. Academic integrity is of central importance in the university community and involves committed allegiance to the values, the principles, and the code of behavior held to be central in that community. Integrity concerns honesty and implies being truthful, fair, and free from lies, fraud and deceit. Cheating or plagiarism is cause for formal university discipline and is justification for an instructor to assign a lower grade or a failing grade.

Academic Integrity and Plagiarism are described and discussed in the University Catalog. This course will be taught in a manner which upholds and enforces those statements. Academic Dishonesty of any sort will not be tolerated and will result in a grade of F for the assignment, quiz, or test, and referral to the Vice President of Student Affairs and to your Dean or Program Director. Dishonesty in this course includes, but is not limited to:

14. Disabled Student Services: CSUDH adheres to the American with Disabilities Act with respect to providing reasonable accommodations for students with temporary or permanent disabilities. To receive accommodations, students with disabilities must register with Disabled Student Services. For more information, please contact their office in Welch Hall B250 at (310) 243-3660 or (310) 243-2028.


15. Statement of Diversity and Inclusion

It is my intent that students from all diverse backgrounds and perspectives be well-served by this course, that students' learning needs be addressed both in and out of class, and that the diversity that the students bring to this class be viewed as a resource, strength, and benefit. It is my intent to present materials and activities that are respectful of diversity: gender identity, sexuality, disability, age, socioeconomic status, ethnicity, race, nationality, religion, and culture. Your suggestions are encouraged and appreciated. Please let me know ways to improve the effectiveness of the course for you personally, or for other students or student groups. Lastly, it is my intention to uphold our class norms. Students who act as a disruption to me or my students will be asked to leave the class.

16. COVID information for students
Stay up to date with and comply with campus COVID polices:

If you get COVID-19:
If you have a positive COVID-19 test and are asymptomatic, or if you get sick and have a positive COVID-19 test, your priority is to get well. Don’t try to tough it out. Get medical attention, quarantine, take care of yourself, recover. Please inform the instructor immediately if you are ill or have an asymptomatic positive COVID-19 test so we can arrange alternate assignments, deferment of deadlines or late penalties, or an incomplete. DO NOT COME TO SCHOOL IF YOU HAVE ANY COVID SYMPTOMS or A POSITIVE TEST RESULT.

Also, report your illness directly to the COVID-19 Reporting Hotline (310) 243-2076, which will be answered by a representative from Human Resources to collect the appropriate information from 9 a.m. to 5 p.m., Monday through Friday. Calls received after hours will be returned the following business day. All information will be kept confidential. The one-stop-shop for COVID resources,  procedures, FAQ’s etc., can be found here:


Date Lecture Reading (Lehninger: Principles of Bicohemistry, 8th Edition) Case Study Homework
January 23

Chemistry of Life / The Cell

Molecules of Life / Water

Ch. 1: Lehninger Introductory Ppt

Ch. 2: Lehninger Water Ppt

Chapter 1



January 25*

Acidosis / Alkalosis

Ch. 2: Lehninger Water Ppt

Chapter 2

Case Study 1 Solution

A Qualitative Look at the HH Equation

Chapters 1 & 2

DUE: Friday, 01/27

January 30

Amino Acids / Proteins

Ch. 3: Lehninger Amino Acids, Peptides and Proteins Ppt

Chapters 3

Case Study 2 Solution

Cys & Lys Structures at Different pH's

Chapter 3

DUE Wednesday, 02/01

February 01

Protein Synthesis and Maturation

Ch. 27: Lehninger Protein Metabolism Ppt

Chapter 27


Chapter 27

DUE: Friday, 02/03

February 06

Proteins: 3D Structure

Ch. 4: Lehninger 3D Structure of Proteins Ppt

Chapter 4

FEAR Protein at Different pH's

Chapter 4

DUE: Wednesday, 02/08

February 08


Ch. 11: Lehninger Membranes Ppt

Chapter 11  

Chapter 11

DUE: Friday, 02/10

February 13

Myoglobin / Hemoglobin

Ch. 5: Lehninger Protein Function Ppt

Chapter 5 Case Study 3 Solution

Chapter 5

DUE: Friday, 02/17

February 15**

Exam 1



February 20 HOLIDAY      
February 22

Enzymes: Catalysis & Kinetics

Ch. 6: Lehninger Enzymes Ppt


Chapter 6

Case Study 4 Solution


February 27

Enzymes: Isozymes & Regulation

Ch. 6: Lehninger Enzymes Ppt

" " Case Study 5 Solution

Chapter 6

DUE: Wednesday, 03/01

March 01

Overview of Nutrients / Vitamins of CHO Metabolism

Intro To & Thermo Of Metabolism

Ch. 13: Lehninger Introduction to Metabolism Ppt

Chapter 13

NADH and FADH2 Structures

Case Study 6 Solution

Chapter 13

DUE: Friday, 03/03

March 06

Study Guide

Overview of CHO Metabolism

Ch. 7: Lehninger Carbohydrates Ppt

Chapter 7  

Chapter 7

DUE: Friday, 03/10

March 08

Exam 2



March 13

Glycolysis, Gluconeogenesis and the PPP

Ch. 14: Lehninger Glycolysis, Gluconeogenesis and the PPP Ppt

Chapter 14


Chapter: 14

DUE: Wednesday, 03/15

March 15#

Citric Acid Cycle

Ch. 16: Lehninger The Citric Acid Ppt

Chapter 16

Case Study 8


Chapter 16

DUE: Friday, 03/17

March 20

Electron Transport

Electron Transport pdf

Ch. 19: Lehninger Oxidative Phosphorylation Ppt

CHO Pathways Review

Chapter 19 Case Study 10 Solution

Chapter 19

DUE: Wednesday, 03/22

March 22#

Glycogen Metabolism

Ch. 15: Lehninger Glycogen Metabolism

Chapter 15

Case Study 9 Solution

Chapter 15

DUE: Friday, 03/24

March 27 HOLIDAY      
March 29 HOLIDAY      
April 03

Fatty Acid beta-Oxidation

Ch. 17: Fatty Acid Metabolism

Chapter 17  

Chapter 17

DUE: Wednesday, 04/05

April 05#

Amino Acid Metabolism

Ch. 18: Amino Acid Metabolism and Urea

Chapter 18    
April 10

The Urea Cycle

Ch. 18: Amino Acid Metabolism and Urea

" "  

Chapter 18

DUE: Friday, 04/14

April 12 Exam 3      
April 17

Nucleotides: Composition and Structure

Ch. 8: Lehninger Nucleotides and Nucleic Acids Ppt

Chapter 8 AT and GC Pair Structures

Chapter 8

DUE: Wednesday, 04/19

April 19#

Ch. 22: Lehninger Nucleotide Synthesis Ppt

Purine Metabolism (Study Guide)

Pyrimidine Metabolism (Study Guide)

Chapter 22


Case Study 7 Solution

Chapter 22

DUE: Friday, 04/21

April 24

DNA Synthesis, Mutation and Repair

Ch. 25: Lehninger DNA Metabolism Ppt

Chapter 25  

Chapter 25

DUE: Wednesday, 04/26

April 26*

RNA Synthesis and Processing

Ch. 26: Lehninger RNA Metabolism Ppt

Chapter 26


Chapter 26

DUE: Friday, 04/28

May 01

Genome Organization

Ch. 24: Lehninger Genes and Chromosomes Ppt

Chapter 24

Study Guide/Worksheet:

Genome Organization

Chapter 24

DUE: Wednesday, 05/03

May 03#

Regulation of Gene Expression

Ch. 28: Lehninger Regulation of Gene Expression Ppt

Chapter 28


Study Guide/Worksheet:


Regulation of Gene Expression

Chapter 28

DUE: Friday, 05/05

May 08 Study Day      
May 10

Exam 4



Monday, May 15 Final Exam, 8:00AM-11:59PM      

*NO Wednesday On-campus Meeting, Lecture will be ON-LINE at 10:00AM Using Class Collaborate Ultra

#NO Wednesday On-campus Meeting, Video is Available on Bb

**NO On-campus Meetings, Exams will be available on-line 8:00AM-11:59PM



Homework Assignment DUE DATE

Log into Blackboard and then navigate to this course.
Click the "Homework" menu link.

Chapters 1 & 2

Friday, 01/27, 2023

Chapter 3

Wednesday, 02/01, 2023

Chapter 27

Friday, 02/03, 2023

Chapter 4 Wednesday, 02/08, 2023

Chapter 11

Friday,02/10, 2023

Chapter 5

Friday,02/17, 2023

Chapter 6

Wednesday, 03/01, 2023

Chapter 13 Friday, 03/03, 2023
Chapter 7 Friday, 03/10, 2023

Chapter 14

Wednesday, 03/15, 2023

Chapter 16

Friday,03/17, 2023

Chapter 19

Wednesday, 03/22, 2023

Chapter 15

Friday, 03/24, 2023

Chapter 17 Wednesday, 04/05, 2023  
Chapter 18

Friday, 04/14, 2023

Chapter 8 Wednesday, 04/19, 2023  
Chapter 22 Friday, 04/21, 2023  
Chapter 25 Wednesday, 04/26, 2023  
Chapter 26 Friday, 04/28, 2023  
Chapter 24 Wednesday, 05/03, 2023  
Chapter 28 Friday, 05/05, 2023  


© Dr. Noel Sturm 2023

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