CHE 450 Syllabus

Date	Lecture	Reading (Lehninger: Principles of Bicohemistry, 7th Edition)	Case Study	Homework
January 25	Chemistry of Life / The Cell Lehninger Introductory Ppt (1-21)	1.1-1.5 2.1, 2.4 & 2.5 10.1, 10.2		Chapter 1 DUE: Friday, 01/29
January 27	Molecules of Life / Water Lehninger Introductory Ppt (22-45) Lehninger Water Ppt (1-36) Lehninger Lipids Ppt (1-24)	2.1, 2.4 & 2.5
February 01	Acidosis / Alkalosis Lehninger Water Ppt (37-51)	2.2 & 2.3	Case Study 1 Solution	Chapter 3 DUE Friday, 02/05
February 03	Amino Acids / Proteins Lehninger Amino Acids Ppt (1-36) Lehninger Proteins Ppt (1-25)	3.1, 3.2 & 3.4 4.1-4.4 pg 172, Sickle Cell Disease	Case Study 2 Solution
February 08	Protein Synthesis and Maturation Lehninger Protein Maturation Ppt (1-48)	27.1 & 27.2		Chapter 27 DUE: Friday, 02/12
February 10	Proteins: Globular and Membrane and Structural (Fibrous) Lehninger Proteins Ppt (26-43)	4.3 5.3
February 15	HOLIDAY
February 17	Membranes Lehninger Membranes Ppt (1-33) Lehninger CHO's Ppt (28-31) Lehninger Lipids Ppt (13-34)	7.3 & 7.4 10.1 & 10.2 11.1-11.3		Chapter 11 DUE: Friday, 02/26
February 22	Myoglobin / Hemoglobin Lehninger Protein Function Ppt (1-34)	4.3 5.1 & 5.2	Case Study 3 Solution	Chapter 5 DUE: Friday, 03/05
February 24	Gas Transport / Antibodies & Antigens Lehninger Protein Function Ppt (35-38)	5.2
March 01	Exam 1
March 03	Enzymes: Catalysis & Kinetics Lehninger Enzymes Ppt (1-11; 22-35)	6.1-6.5	Case Study 4 Solution
March 08	Enzymes: Isozymes & Regulation Lehninger Enzymes Ppt (36-42)	" "	Case Study 5 Solution	Chapter 6 DUE: Friday, 03/12
March 10	Enzyme Mechanisms-Serine Proteases Lehninger Enzymes Ppt (12-21)	" "
March 15	Overview of Nutrients / Vitamins of CHO Metabolism Cobalamin, Folic Acid, Antioxidants Lehninger ThermoMetabolism Ppt (16-21) Lehninger Lipids ppt (35-41)	13.4	NADH and FADH₂ Structures Case Study 6 Solution
March 17	Nucleotides: Composition and Structure Lehninger Nucleotides Ppt (1-38) Lehninger Lipids ppt (23-29)	8.1-8.4	AT and GC Pair Structures	Chapter 8 DUE: Friday, 03/19
March 22	Exam 2
March 24	Purine Metabolism (Study Guide) Pyrimidine Metabolism (Study Guide) Lehninger Nucleotide Synthesis Ppt	pg. 900 Lesch-Nyhan	Case Study 7 Solution
March 29	Spring Break
March 31	Spring Break
April 05	DNA Synthesis Lehninger DNA Ppt (1-37)	24.1-24.3		Chapter 25 DUE: Friday, 04/09
April 07	DNA Mutation and Repair Lehninger DNA Ppt (38-55) RNA Synthesis and Processing Lehninger RNA	25.1 & 25.2 26.2
April 12	Genome Organization Lehninger Genes Ppt	24.3	Study Guide/Worksheet: Genome Organization
April 14	Regulation of Gene Expression Lehninger Genome Organization	28.1-28.3	Study Guide/Worksheet: Regulation of Gene Expression
April 19	Study Guide Overview of CHO Metabolism Lehninger CHO Ppt (1-22)	7.1 & 7.2
April 21	Intro To & Thermo Of Metabolism Glycolysis Lehninger Thermodynamics in Metablism Ppt (1-15) Lehninger Glycolysis Ppt (1-39)	1.3 13.1 14.1-14.3		Chapter: 14 DUE: Friday, 04/23
April 26	Exam 3
April 28	Citric Acid Cycle Lehninger Citric Acid Ppt (1-28)	16.1-16.3	Case Study 8 Solution	Chapter 16 DUE: Friday, 05/07
May 03	Glycogen Metabolism Gluconeogenesis Lehninger Carbohydrates Ppt (23-27) Lehninger Gluconeogensis and PPP Ppt (40-50)	7.2 14.4 & 14.5 15.4 & 15.5	Case Study 9 Solution
May 05	Electron Transport Electron Transport pdf Lehninger Electron Transfer Ppt (1-20) Pathways Review	19.1-19.3	Case Study 10 Solution	Chapter 19 DUE: Friday, 05/14
May 10	Study Day
May 12	Exam 4
Monday, May 17	Final Exam, 10:00AM-12:00PM

Homework Assignment	DUE DATE	Log into Blackboard and then navigate to this course. Click the "Assignment" menu link.
Chapter 1	Friday, January 29^th, 2021
Chapter 3	Friday, February 5^th, 2021
Chapter 27	Friday, February 12^th, 2021
Chapter 11	Friday, February 26^th ,2021
Chapter 5	Friday, March 5^th, 2021
Chapter 6	Friday, March 12^th, 2021
Chapter 8	Friday, March 19^th, 2021
Chapter 25	Friday, April 9^th, 2021
Chapter 14	Friday, April 23^rd, 2021
Chapter 16	Friday, May 7^th, 2021
Chapter 19	Friday, May 14^th, 2021